For laboratories that need an LC and entry-level UHPLC compatible system, and are in the process of adapting UHPLC methods. Typical application areas are QA/QC for pharmaceutical, food and beverage, and personal care products, as well as environmental method development and academic research. Especially recommended for methods where short (up to 100mm length), sub-2µm particle columns are used (fast cycle times) and where fast gradient response is mandatory (i.e., LC-MS). This is the system of choice for when smaller column internal diameters as low as 1mm are planned to be used but also conventional 2.1 to 4.6mm columns with core enhanced particle technology or conventional 3–5µm porous particle columns need to be supported. In academic, food and beverage, and pharmaceutical research, the system excels by mastering discovery type assays as well as purification and target component isolation runs within the research process.

Ensuring Excellent Chromatography

• Up to 10 mL/min flow rate supporting up to 62 MPa (9000 psi/620 bar) backpressure for column format and column particle size flexibility

• Get near-zero dead volume connections for optimal peak shapes even over extended periods by using Thermo Scientific™ Dionex™ Viper™ Fingertight fitting system

• Minimize contamination between samples for more accurate results using ultra-low carryover autosamplers (with loop and needle permanently in the flow path)

• Get precise and accurate flow rates for stable retention times, robust peak integration, and confident identification using Thermo Scientific™ Dionex™ SmartFlow™ technology

• Optimize mixing efficiency with adjustable gradient delay volumes using Thermo Scientific™ Dionex™ SpinFlow™ technology

• Transfer methods between systems with confidence; this system shares an identical system delay volume with the Thermo Scientific™ Dionex™ RS Binary System by design

  Chromeleon CDS Software Makes Operation Easy

• Integrated service and validation monitoring with Thermo Scientific™ Dionex™ Chromeleon™ versions 6.x and 7.x

• Automated system startup, standby and shutdown with Chromeleon versions 6.x and 7.x

• Compatible with Chromeleon 7.x eWorkflow™ walk-up solution and advanced reporting features

  Choose the Right Configuration for You

• Two- or four-solvent channel pump design, two solvents at a time only (HPG-3200RS or HPG-3400RS)

• Two- or four-channel degasser integrated in solvent rack (SRD-3200 or SRD-3400)

• With thermostatted or nonthermostatted autosamplers (WPS-3000TSL/WPS-3000SL)

• Thermostatted column compartment with up to 2 field upgradable column switching valves, (TCC-3000RS)

• Diode array, multiple wavelength, variable wavelength, fluorescence, charged aerosol, refractive index or mass spectrometry detectors

• Fraction collector (AFC-3000)

• Chromeleon 7.2 software packages (networked, standalone, remote data processing and/or control)